The answer is yes.

Robert Downey Jr. in his Doctor Doom outfit at SDCC 2024 next to Iron Man in the MCU and Doctor Doom in Fox’s Fantastic Four

galactus towering above earth with his own floating skull

Black Knight and Thor fight back to back with each other.

Robert Downey Jr. as Tony Stark in Iron Man 3 (2013) next to artwork of Doom from Marvel Comics

Custom Image by Lewis Glazebrook

Robert Downey Jr. holding his Doctor Doom mask above blurred artwork of the Dark Avengers

Custom Image by Lewis Glazebrook

Comics